Skin and Hair

Melagol Gel

Melagol 3d

Indications

Acne, Acne Vulgaris .

Dosage

Apply a thin layer of Melagol gel on the affected area of skin two times a day.

Contraindication

Side Effects: In sensitive patients to herbal products may cause allergic contact dermatitis.

Contraindications: Melagol Gel should definitely not be applied on eczematous skin as it can cause irritation.
Pregnancy and Lactation: No limitation.

Composition

Each 100 g Gel contains tea tree oil (Melaleuca alternifolia) 5g , along with other effective component against acne such as distilled water of Lavandula, salvia officinalis , rosemary, Hamamelis, Melissa officinalis and the oils of bergamot, chamomile, Mentha piperita.

Constituents

Tea tree oil : terpinene – 4- ol, gamma – terpinene, alpha – terpinene, 1.8- cineole, alpha- terpineol, alpha – pinene, limonene, p-cymol, terpinolene, viridiflorene .
Other important ingredients are: flavonioids, salviatannin, rosmarinic acid, carnosol, menthol and caradin.

Drug Form

Gel 30 mg

Pharmacological actions

Of all the herbal acne treatments, tea tree oil has been shown to be the most effective and has been studied for
effectiveness in a clinical trial (1,2,3) .
The strong antibacterial properties possessed by tea tree oil (TTO) made it extremely effective in treating those suffering from varying degrees of acne issues(4). This natural acne remedy is well tolerated by the skin making it possible for all skin types to achieve favorite results from adding to their daily skin care routine . Applying Melagol Gel 2 -3 times a day regularly is the most effective way to get rid of acne problems. A broad range of bacteria have now been tested for their susceptibilities to TTO. While most bacteria are susceptible to TTO at the concentration of 1.6% or less, TTO in excess of 2% have been reported for organisms such as skin staphylococci and micrococci , Enterococcus Faecalis and pseudomonas aeruginosa, TTO is for the most part bactericidal in nature, although it may be bacteriostatic at lower concentrations.
The mechanism of action of TTO against bacteria has now been partly elucidated. The mechanism of antibacterial action of TTO is the loss of intracellular
material, inability to maintain homeostasis, and
inhibition of respiration after treatment with TTO and / or the loss of membrane integrity and function (5,6).
A 5% solution of tea tree oil was effective in treating
acne vulgaris in a study of 124 patients who were randomized to receive either tea tree oil or 5% benzoyl peroxide lotion for 3 months. Both groups showed improvement in the number of inflamed lesions, the number of noninflamed lesions, and skin oiliness (5). However, significantly fewer overall side effects were reported by the TTO group .

Reference

1. Finally, the Acne Mystery Solved. http://www.acneyoda.com.
2. Herbal Treatment for acne. http://www.skinhelp.co.uk/Herbal treatments for Acne.html.
3. Acne Treatment. Natural Acne treatment. http://www.10acnetreatments.com/teatree-oil.html.
4. Melaleuca alternifolia (Tea Tree) oil: a Review of Antimicrobial and other Medicinal properties, Clinical Microbiology Reviews.19(1): 50-62.(2006).
5. Bassette, I.B., Pnnowitz, D.L and Barnetson, R.S. A comparative study of tea-tree oil versus benzoyl peroxide in the treatment of acne.Med.j.AUS. 15; 153(8): 455-8.(1990).
6. Tea Tree oil Melaleuca.http://www.Cosmeticscop.com/skin-core- facts-tea-tree-oil-melaleuca0oil-acne-treatment.
7. Tea Tree oil for Acne.http://altmedicine.about.com/b/2008/06/30 tea-tree- oil-for-acne.htm.
8. Enshaie, S., Jooya, A., Siadat, A. H. and Iraji, F. The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: A randomized, double-blind placebo- Controlled study. Indian Journal of Dermatology venerology and leprology, Vol.73, 22-25.(2007).
9. Tea Tree oil for Acne.http://www.christianet.com/acne/teatreeoilforanc e.htm.
10. Thompson G. and et al. A randomized Controlled trial
of tea tree oil (5%) body wash versus standard body wash to prevent colonization with methicillin resistant staphylococcus aureus (MRSA) in critically ill adults; research protocol. BMC Infectious Diseases, 8:167.(2008).