As an antiphlogistic for inflammation of the gum and the mucous membranes of the mouth and throat , for gingivitis and stomatitis.
Apply about 1 cm gel on the mouth mucosa and rub with finger tip 3 times a day.
Packaging : Tube of 15 g gel .
It is not recommended during pregnancy. In lactation period it should be used with caution.
Side effects :
Extra use of Salvizan gel may lead to dryness of the mouth. In sensitive individuals to plant material may induce sensitization.
Other therapeutic effects :
Salvizan gel can be used in aftus , stomatitis, gingivitis, glossitis and laringitis.
Each 15g of Salvizan gel contains 28% hydroalcoholic extract of salvia officinalis ( sage leave ) ( 1: 2 ratio ).
Sage leave contains 3-8% condensed catechin–type tannins (Salviatannin ) : phenolic acids ( Rosemarinic , caffeic , chlorogenic , ferulic and gallic acids ) ; 1-3% flavonoids ( apigenin and luteolin derivatives ) : volatile oil (monoterpenoids , α – thujone
- thujone , camphor , cineole , humulene , α pinene camphene , limonene , bornyl acetate and carnosol.
The surfaces at the back of the mouth and pharynx are the first point of contact for ingested or inhaled pathogens and irritants ; the dense masses of lymphatic tissue in the region confirm their important role in defence. Salvizan gel appears to mobilize activity in the surrounding lymphatic tissues , through its active constituents (1).
It has been experimentally proven that sage products is astringent , antiseptic and disinfectant ( against inflammation ). It is antibacterial ( 1,2,3 ) fungistatic , virustatic stimulating and can be used in mouth rinses and gargles for inflamed tissue of the oral cavity and throat ( 1,2 ).
It`s volatile oil has antimicrobial activity attributed to its thujone content ( 3,4,5 ).
In Germany , sage is licensed as a standard medicinal tea which is applied topically as a rinse or gargle for inflammation of mouth and throat (6).
The combination effects of antiphlogestic , antiseptic fungistatic explain the mechanism of action of this drug.
11.Jalsenjak V, Pelingak , S,Knstrak , D . 1987 Microcapseles of sage oil : Essential oils content and antimicrobial activity . Pharmazie 42 ( 6) : 419 – 420 .
2. Todorovs . 1994 Experimental Pharmacological study on saliva . Acta Phsiol Pharmacol Bulg 13-20 .
3. Newall , C. A., L.A . Anderson . J. D. Philipson . 1996 Herbal Medicines ; Guide for Health Care Professionals London ; The Pharmaceutical press.
4. Jalsenjak, V. S. Pelinjak , D. Kustrak , 1987. Microcapsules of sage oil : Essential oils content and antimicrobial activity , Pharmazie 42 (6) : 419 – 420.
5. Karnick, C.R. 1994. Pharmacopoeial standards of Herbal plants ; Delhi ; Sri satguru Publications. Vol 1 : 324 – 325 , Vol 2 : 114 .
6. Wichtl, M. and N.G. Bisser. 1994 Herbal Drugs and Phytopharmaceuticals ; Stuttgart : Medpharm Scientific Publishers.