Kidney and Urinary Tract Diseases

Powergol Capsule

Powegol 3d

Indications

Impotence, Erectile dysfunction

Dosage

 Take one capsule two hours before intercourse Maximal dosage is 2 capsules a day .

Contraindication

Heart patients should use this formulation under the supervision of a clinician . Patients under treatment with narcotics, anti-epilepsy drugs avoid taking this product .

 Side Effects :  Sensitive individuals to herbal drugs or essence may see allergic reactions .

Composition

 Dry extracts of Saw palmetto (serenoa  repens L), Turnera diffusa L.

(Damiana) , Panax ginseng , pausinystalia yohimbe L. , Royal jelly, vitamin C, E. Zn and selenium .

Drug Form

Capsule: Boxes of 30 capsules 

Stands On

The basis of 4.5 – 5.5 mg Yohembine . hydrochloride in each capsule   .

Pharmacological actions

Most research in erectile dysfunction (ED) focused on peripheral neurophysiology and on the local tissues of the penis, there has, however, been growing interest in the role of the central nervous system (CNS) in the control of erectile function. An erection is a carefully orchostrated series of events controlled by CNS. It is known that the penis is under the complete control of the CNS, both during sexual arousal and at rest. Any disturbance in the network of nerve pathways that connects the penis and the CNS can lead to problems with erections . Oxytocin is an important neurotransmitter in men, with powerful proerectile effects, as it activates excitatory nerve pathways from the spinal erection – generating center to the penis . Powergol  formulation supports genital blood flow for sexual function . Damiana plant extract increases sexual function . There is some evidence to support for its use in impotency and decreased sexual  functioning (1). Panox ginseng was found to be an effective alternative to the invasive approaches for treating erectile dysfunction (ED). This was demonstrated in a double – blind, placebo – controlled study of 60 patients with mild or mild – to – moderate ED (2) .

Yohimbine is a relatively safe medication that has beneficial effect in the management of ED. Because of the alpha – 2 adrenergic blockade, the drug may be an effective treatment for sexual side effects, such as decrease libido and decreased sexual response, caused by selective serotonin reuptake inhibitors(5) .

Saw palmetto is considered as a sexual stimulant, aphrodisiac and has been used as a sexual stimulant and aphrodisiac for long.

Royal jelly is rich in amino acids(29amino acids), lipids, sugars, some vitamins, fatty acids and most importantly, proteins. It contains  ample levels of iron and calcium . Royal jelly also contains acetylcholine which is a neurotransmitter involved in sexual function – Also, it increases libido and support egg and sperm health , acts as a nutritive energy tonic and boost testosterone which help to treat ED . Royal jelly has been shown to have positive effects on impotence in men .

Reference

  1. Arleltti R. et al. Stimulating property of Turnera diffus and Pfaffia paniculata extracts on the sexual behavior of male rats . Psychopharmacology 143 (1) : 15 – 19. 1999 .

     2. De Andrade E, et al. Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction. Asian J Androl ; a (2): 241 – 244. 2007 .

     3. Hollander E, Mc carley A, Yohimbine treatment of sexual side effects induced by serotonin reuptake blockers. I. Clin Psychiatry, 53(6):207 -9 , 1992.